Novel immune scoring dynamic nomograms based on B7-H3, B7-H4, and HHLA2: Potential prediction in survival and immunotherapeutic efficacy for gallbladder cancer

BackgroundGallbladder cancer (GBC) is a mortal malignancy with limited therapeutic strategies.We aimed to develop novel immune scoring systems focusing on B7-H3, B7-H4, and HHLA2.We further investigated their potential clinical effects in predicting survival and immunotherapeutic efficacy for GBC.MethodsThis was a retrospective cohort study in a si

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Mechanism of hydrogen isotope exchange for tritium removal in plasma-facing materials: a multi-scale investigation

The safety of future fusion reactors is critically dependent on the tritium (T) retention in plasma-facing materials.Hydrogen isotope (HI) exchange offers a method to redistribute HIs within solid materials, presenting a feasible approach for removing T from bulk materials and trapped by strong trapping sites.Nonetheless, unraveling the intricate m

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Managing Soils for Recovering from the COVID-19 Pandemic

The COVID-19 pandemic has disrupted the Generator W/ Plastic Battery Bracket global food supply chain and exacerbated the problem of food and nutritional insecurity.Here we outline soil strategies to strengthen local food production systems, enhance their resilience, and create a circular economy focused on soil restoration through carbon sequestra

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